Lisa A. Prosser, PhD; Rafael Harpaz, MD, MPH; Angela M. Rose, MPH; Acham Gebremariam, MS; Angela Guo, MPH; Ismael R. Ortega-Sanchez, PhD; Fangjun Zhou, PhD; Kathleen Dooling, MD, MPH
A new herpes zoster subunit vaccine, recombinant zoster vaccine, was approved in 2017 to prevent shingles and complications. This analysis evaluates the cost-effectiveness of that vaccine.
Jiapeng Lu, MD, PhD; Yuan Lu, ScD; Hao Yang, BSc; Wuhan Bilige, MB; Yetong Li, BSc; Wade Schulz, MD, PhD; Frederick A. Masoudi, MD, PhD; Harlan M. Krumholz, MD, PhD
Although cardiovascular disease (CVD) accounts for 40% of deaths in China, information on the risks for CVD and how to manage it is lacking. This study of more than 1 million persons assessed the prevalence and treatment of those with high cardiovascular risk.
Pontus Henriksson, PhD; Hanna Henriksson, PhD; Per Tynelius, MSc; Daniel Berglind, PhD; Marie Löf, PhD; I-Min Lee, MBBS, ScD; Eric J. Shiroma, ScD; Francisco B. Ortega, PhD
The relationship between a healthy lifestyle during adolescence and chronic disease later in life is not well understood. This study, which involved a large cohort of male adolescents in Sweden, examined the relationship of cardiorespiratory fitness and obesity with receipt of a disability pension later in life.
Deborah Mascalzoni, PhD; Heidi Beate Bentzen, LLM; Isabelle Budin-Ljøsne, PhD; Lee Andrew Bygrave, LLD; Jessica Bell, PhD; Edward S. Dove, PhD; Christian Fuchsberger, PhD; Kristian Hveem, MD, PhD; Michaela Th. Mayrhofer, PhD; Viviana Meraviglia, PhD; David R. O'Brien, JD; Cristian Pattaro, PhD; Peter P. Pramstaller, MD; Vojin Rakić, PhD; Alessandra Rossini, PhD; Mahsa Shabani, PhD; Dan Jerker B. Svantesson, PhD; Marta Tomasi, PhD; Lars Ursin, PhD; Matthias Wjst, MD; Jane Kaye, DPhil
New efforts and requirements to deposit data in research repositories are necessary to protect privacy interests and comply with the European Union's General Data Protection Regulation. The authors discuss some of the conflicts involved and why they must be reconciled to support ethical and lawful data sharing.
Heidi Beate Bentzen, LLM; Njål Høstmælingen, LLM
The health care community is concerned that the General Data Protection Regulation, a recently adopted European Union data privacy law, may impede the flow of information needed to facilitate research and improve care. The authors address these concerns and contend that the regulation specifically aims to facilitate the free movement of data within the European Union rather than restrict or prohibit it.
Rhanderson Cardoso, MD; Khurram Nasir, MD, MPH, MSc; Roger S. Blumenthal, MD; Michael J. Blaha, MD, MPH
This commentary addresses the 2018 American Heart Association and American College of Cardiology risk assessment and cholesterol management recommendations about “risk enhancers” and coronary artery calcium testing.
Paul K. Whelton, MB, MD, MSc; Lisandro D. Colantonio, MD, PhD
Lu and colleagues estimated the prevalence of high cardiovascular disease (CVD) risk in a cohort of almost 1.7 million Chinese adults aged 35 to 75 years with no history of a CVD event. The editorialists see their findings as an important call to action for highly populated middle- and low-income countries in which worsening of the CVD risk factor profile is outpacing the current health sector response.
Stephen D. Shafran, MD
In their article, Prosser and colleagues evaluate the cost-effectiveness of recombinant zoster vaccine compared with zoster vaccine live and no zoster vaccination. The editorial discusses the findings in light of current immunization recommendations.
Jessica Zitter, MD, MPH
There was relief in knowing that my colleague could offer what this woman needed even when I couldn't—especially when I couldn't.
Richard B. Weinberg, MD
“Children don't fear death—they fear pain and abandonment. Even the wee ones can sense who can give them shelter.”
Lawrence J. Hergott, MD
Henry S. Sacks, PhD, MD, FACP, FIDSA
William G. Herrington, MD; Doreen Zhu, MBChB; Richard Haynes, DM
Roger R. Dmochowski, MD, MMHC, FACS
Bruce E. Johnson, MD
Christine F. McDonald, MBBS, PhD; Christopher J. Worsnop, MBBS
Xavier Calvet, MD, PhD
Gregory E. Simon, MD, MPH
Reza Mirza, MD; Gordon Guyatt, MD
Joseph F. Rappold, MD, FACS
Adam J. Nelson, MD; Christopher B. Granger, MD
Geno J. Merli, MD; Howard H. Weitz, MD
Annals Consult Guys brings a new perspective to the art and science of medicine with lively discussion and analysis of real-world cases and situations. They address medically relevant topics—whether they be poignant, thought-provoking, or just plain entertaining.
Darren B. Taichman, MD, PhD
David H. Wesorick, MD; Vineet Chopra, MD, MSc
Pramod K. Garg, MD
This commentary discusses management of patients who present to the hospital with acute pancreatitis.
Robert M. Centor, MD; Gustavo R. Heudebert, MD
In this episode of Annals On Call, Dr. Centor discusses the estimation of stroke risk in patients with atrial fibrillation with Dr. Gustavo Heudebert, a professor of medicine at the University of Alabama.
Michael Natter, MD
Progress Notes explores the everyday emotional, clinical, humorous, and ethical challenges of the medical residency training process. It appears monthly in Annals Graphic Medicine at Annals.org.
Christopher L. Bennett, MD, MA
Annals Graphic Medicine brings together original graphic narratives, comics, animation/video, and other creative forms by those who provide or receive health care. They address medically relevant topics##mdash;whether they be poignant, thought-provoking, or just plain entertaining.
Ian Barnett, PhD; John Torous, MD
Artificial intelligence and machine learning promise to improve health care and health itself, but potential pitfalls exist. A recent example is Facebook's efforts to screen users' posts to identify those at risk for suicide and alert emergency services.
K.M. Venkat Narayan, MD; Shivani A. Patel, PhD; Solveig A. Cunningham, PhD; James Curran, MD
This commentary describes the recent reversal of health gains in the United States due to increases in midlife mortality rates among many groups. The authors' solution is to equally emphasize research and allocate resources on biological, socioeconomic, and political determinants of health.
Robert E. Brutcher, PharmD, PhD; Connie Kurihara, RN; Mark C. Bicket, MD; Parvaneh Moussavian-Yousefi, PharmD; David E. Reece, MD; Lisa M. Solomon, BS; Scott R. Griffith, MD; David E. Jamison, MD; Steven P. Cohen, MD
The use of compounded topical pain creams has increased dramatically, yet their effectiveness has not been well evaluated. This trial assessed the effectiveness of compounded creams versus placebo for treating localized chronic pain.
Christopher E. Cox, MD; Douglas B. White, MD; Catherine L. Hough, MD; Derek M. Jones, MDiv; Jeremy M. Kahn, MD; Maren K. Olsen, PhD; Carmen L. Lewis, MD; Laura C. Hanson, MD; Shannon S. Carson, MD
Patients requiring prolonged mechanical ventilation face high morbidity and mortality and frequently lack decisional capacity. Decision aids might help align surrogate decision makers and clinicians' understanding of patient prognosis to better inform discussions regarding plans of care. This randomized trial assessed whether a decision aid improved agreement between surrogates' and clinicians' assessments of patient prognoses.
Aaron M. Tannenbaum, MD; Scott D. Halpern, MD, PhD
In their article, Cox and colleagues examine whether a surrogate-facing decision aid improves clinician–surrogate concordance on estimates of 1-year survival or any of several patient and surrogate outcomes for patients receiving prolonged mechanical ventilation and find no such benefits. The editorialists posit that interventions that merely enhance knowledge and induce deliberation may never promote better surrogate decision making.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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